View the Colts' 2025 schedule here .

1. A 21-season streak comes to an end.

Let's begin at the finish with the Colts' Week 18 season finale against the Houston Texans at NRG Stadium. That game will be the first time the Colts finish a season against the Texans in Houston since 2003, ending a somewhat odd 21-season streak.

The Colts won that game on Dec. 28, 2003, by the way, with Edgerrin James rushing in a touchdown and Peyton Manning finding Brandon Stokley for a score to erase a 14-point fourth quarter deficit before Mike Vanderjagt hit a 43-yard field goal as time expired for a 20-17 win.

With this game against the Texans, too, the Colts will go at least seven seasons without facing the Tennessee Titans to end a season. The last time the Colts ended their season against the Titans

See Full Page