Pick a cancer that you’d like to investigate. There’s a good chance that you can now pull up that cancer’s proteome. And if you can’t, researchers have made major inroads that are paving the way for proteomic maps for more than 200 described cancers.
An international collaboration of four cancer proteomics laboratories and their clinical partners released The Pan-Cancer Proteome Atlas (TPCPA), the most comprehensive tumor protein map to date. In a research article published today in Cancer Cell , the massive dataset catalogs nearly 10,000 proteins across 999 primary tumors from 22 cancer types, providing a high-resolution view of the molecular machinery driving cancer. The atlas has revealed promising new cancer drugs and diagnostic targets, including precision therapies for c