Researchers at Mass General Brigham have developed a new diagnostic method that significantly enhances virus detection by harnessing bioluminescence. The tool, called the Luminescence CAscade-based Sensor (LUCAS), was designed to be portable, fast, and highly sensitive and is capable of diagnosing SARS-CoV-2 , HIV , hepatitis B (HBV), and hepatitis C (HCV) with over 94% accuracy in less than 23 minutes. Details of the new point-of-care diagnostic tool are published in Nature Biomedical Engineering .
“Developing effective diagnostics is incredibly challenging, especially when you think about the size of infectious disease particles and the complicated biological fluids we’re attempting to identify them in,” said senior author Hadi Shafiee, PhD, an associate professor of Medicin