Researchers have uncovered the potential role of gut microbes in the early detection and monitoring of colorectal cancer (CRC) in a groundbreaking international study. By analyzing stool samples from over 3,700 individuals across 18 international cohorts, the study mapped microbial changes associated with cancer stages, tumor location, and progression, refining our understanding of the microbiome as a diagnostic and prognostic tool for one of the deadliest cancers worldwide. The study , published in Nature Medicine , holds promise for improving non-invasive stool tests, which could revolutionize the way CRC is detected and treated.

CRC stage-specific microbiome landscape

CRC is the third most common cancer globally and the second leading cause of cancer-related deaths. Althou

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