MedPage Today
Key Takeaways
Anti-anxiety drugs, sedatives, or antidepressants were linked with a higher risk of subsequent ALS diagnosis.
ALS patients who used anxiolytics or antidepressants before their diagnosis had shorter survival times.
Findings may reflect associations between psychiatric symptoms and ALS risk.
Prescribed use of anti-anxiety drugs, hypnotics and sedatives, or antidepressants was tied to a higher future risk of amyotrophic lateral sclerosis (ALS) diagnosis and a poorer prognosis, a case-control study in Sweden showed.
Excluding the year before diagnosis from the analysis, prescriptions for anxiolytics (OR 1.34, 95% CI 1.12-1.60), hypnotics and sedatives (OR 1.21, 95% CI 1.02-1.43), or antidepressants (OR 1.26, 95% CI 1.06-1.49) were associated with increased ALS risk, reported
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