Princess Margaret Cancer Foundation will be hosting its 18th annual The Ride to Conquer Cancer this weekend.

This edition of “Canada’s largest athletic fundraiser” is presented by Johnson & Johnson and also partners with regional businesses such as Peller Estates wines and McMaster University.

Hamilton and Niagara are expected to host more than 4,000 cyclists over the weekend.

Participants include first-time riders, 18-year veterans of the fundraiser and cancer survivors (who ride with yellow flags).

Funds raised go toward cancer research, helping fight a disease that will affect two in five Canadians during their lifetimes, according to a Princess Margaret press release.

The ride has a variety of options for routes, and has one- or two-day riding options. The most popular route, The

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