Both looking to squeeze into the knockout rounds of the competition, LDU Quito and Central Cordoba clash at Estadio Rodrigo Paz Delgado in the Copa Libertadores on Wednesday night.
La Casa Blanca have suffered a difficult period on the domestic front of late, whilst El Ferroviario are set to defy pre-season expectations.
Match preview
After enjoying a six-game unbeaten run from the middle of April to the middle of May, LDU Quito have endured somewhat of a tricky patch across all competitions, collecting just a single point across matches in the Ecuadorian Serie A and the group stage of the Copa Libertadores.
La Casa Blanca were last in action on the domestic scene on Saturday afternoon, when goals from Mauro Diaz and Jose Fajardo helped Universidad Catolica to a 3-1