Wales will hope to maintain their place at the top of their World Cup qualifying group when they travel to play at Stade Roi Baudouin on Monday.
Fourth-placed Belgium drew their only game in their five-team group so far against North Macedonia on Friday, while Wales have seven points after three matches and beat Liechtenstein 3-0 on May 6.
Match preview
The hosts were held to a 1-1 stalemate by North Macedonia, with both sides creating two big chances, though Belgium registered just one shot on target in the second half.
De Rode Duivels have only kept one clean sheet in their past 10 matches while also failing to score in two of their last five.
Belgium are undefeated in three clashes against Wales, but they only triumphed once in that time, drawing four and losing two of their