More widespread and consistent use of pre-exposure prophylaxis (PrEP) has the potential to dramatically reduce the incidence of HIV in the U.S., but substantial barriers to PrEP remain, particularly access, stigma, and non-HIV specialist physicians' knowledge of the growing slate of options.

New PrEP options on the horizon may help alleviate some of these barriers as physician awareness also increases.

"There's data from contraception [studies] that if you have more choice, the uptake is higher overall," Matthew Spinelli, MD, of the University of California San Francisco, told MedPage Today . "PrEP is highly effective, and if the populations that need it had access to it, we would see the end of the HIV epidemic."

A 2022 study modeled HIV transmission in 32 U.S. urban areas and used

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