TOPLINE:

The incidence of appendiceal adenocarcinoma in the United States more than tripled among those born in 1980 and rose more than fourfold among those born in 1985 compared with a cohort born in 1945, a study found. Greater recognition of appendix cancer as distinct from colon cancer could partly explain the results, but generational differences in exposures affecting cancer risk are also possible, the researchers said.

METHODOLOGY:

A retrospective cohort study analyzed 4858 cases of pathologically confirmed primary appendiceal adenocarcinoma diagnosed between 1975 and 2019 in patients aged 20 years or older from eight population-based cancer registries in the United States.

Researchers used data from the National Cancer Institute’s Surveillance, Epidemiology, and End Results Pro

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