TOPLINE:

Although cardiovascular disease (CVD)-related mortality decreased significantly from 1999 to 2020 in both men and women with immune-mediated inflammatory diseases (IMIDs), women consistently had higher rates of CVD-related mortality than men over the 22-year period.

METHODOLOGY:

Researchers analyzed CDC Multiple Cause of Death files from 1999 to 2020 to assess the sex differences in CVD-related mortality in patients with IMIDs.

They identified CVD-related deaths with underlying IMIDs in the United States using diagnostic codes.

IMIDs such as rheumatoid arthritis, systemic lupus erythematosus, and systemic sclerosis were analyzed.

The analysis included 281,355 IMID-related deaths and 127,149 CVD-related deaths over a period of 22 years.

Annual crude and adjusted death rates

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