SEATTLE -- Low-sodium oxybate (Xywav) reduced blood pressure as expected compared with the higher-sodium version (Xyrem), reduced nocturnal arousal, and appeared safe at doses above 9 g, a series of studies in narcolepsy and idiopathic hypersomnia showed.

The studies were reported together at a late-breaking science session at the SLEEP meeting hosted jointly by the American Academy of Sleep Medicine and the Sleep Research Society.

Altogether, the data were reassuring and present a pretty appealing picture of advantages of low-sodium oxybate over the similarly dosed standard version, commented session moderator Remy Roque, MD, of Emory University in Atlanta.

"The low-sodium one is available and it's accessible. It's most likely the better option for most people," he told MedPage Toda

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