The Philadelphia Phillies go for the three-game series sweep when they meet the Baltimore Orioles in a key interleague series on Wednesday afternoon. Philadelphia earned a 13-3 win on Monday and followed that up with a 5-0 victory on Tuesday. The Orioles (51-63), who have lost three in a row, are 24-36 on the road this season. The Phillies (65-48), who are on a three-game winning streak, are 37-20 on their home field in 2025.

First pitch from Citizens Bank Park in Philadelphia is set for 12:35 p.m. ET. The Phillies have won seven of the last 10 meetings with the Orioles. Philadelphia is a -161 favorite on the money line (risk $161 to win $100) in the latest Orioles vs. Phillies odds from DraftKings Sportsbook , while the total number of runs Vegas thinks will be scored, or the over-

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