Rates of early-onset gastrointestinal cancers, including stomach, pancreatic, and colorectal malignancies, have been on the rise in adults younger than 50 years. In the United States, the rates of colorectal cancer in adults 50 years and older have been stabilizing, while they are increasing in younger adults. Colorectal cancer is now the leading cause of cancer deaths in men younger than 50 and the second leading cause in women younger than 50. Breast cancer remains the number one cause of cancer deaths in younger women.

In 2021, the U.S. Preventive Services Task Force reduced the recommended age for colorectal cancer screening from 50 to 45 years. Still, the percentage of people aged 45 to 49 participating in screening remains concerningly low (less than 2%).

Several types of tests can

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