Chronic fatigue syndrome or myalgic encephalomyelitis ( ME/CFS ) is a debilitating and long-neglected disease that experts typically dismissed as psychosomatic for decades.

To this day, some physicians still believe the illness is all in a patient's head, but the largest genetic analysis of its kind suggests there are real biological origins.

A UK research project, called DecodeME, has investigated the genome-wide associations and uncovered eight possible signals associated with ME/CFS.

The preprint findings, which have not yet been published or peer-reviewed, suggest that an individual's genes at least partly contribute to their chances of developing ME/CFS.

Related: Long COVID Fatigue Shows Up as Distinct Changes in Brain Scans

One of the eight genetic variants "nicely ove

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