Cleveland Browns fans will get their first look at rookie quarterback Shedeur Sanders on Friday night when the team takes on the Carolina Panthers.

The total sits at 32.5 points for this matchup, while the point spread hovers around 6.5 points, in favor of the Panthers (-265 moneyline odds).

Can Cleveland (+240) go on the road and get a preseason Week 1 win with several injuries to key players and a rookie under center?

Browns vs. Panthers Predictions and best bets

Under 32.5 points

Neither the Panthers nor the Browns have been closely associated with offensive output over the past few seasons.

In fact, Cleveland was dead last in points per game, while the Panthers were 29th in total yards per game in 2024.

For this matchup, Bryce Young is expected to play one or two series whil

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