San Diego Padres left fielder Ramon Laureano (5) celebrates with third baseman Manny Machado (13) after hitting a walk-off single during the tenth inning against the Boston Red Sox at Petco Park in San Diego Aug. 9.

The San Diego Padres (66-52) face the San Francisco Giants (59-59) in the opener of a 3-game set Monday. First pitch from Oracle Park in San Francisco is set for 9:45 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the Padres vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 4-2

The Friars took 2 of 3 from the Boston Red Sox over the weekend, culminated by a 6-2 winner Sunday. DH Luis Arraez went 2-for-4 with 2 RBIs. He had 2 hits in each game of the series over the weekend and is hitting .295 on the season. The Padres have won 4 of 5 and sit 2 games back in the NL West and are in the second Wild Card spot.

The Giants dropped 2 of 3 to the Washington Nationals over the weekend with an 8-0 stinker Sunday. RHP Justin Verlander became the 10th player in MLB history with 3,500 strikeouts, but he was shelled for 5 ER on 11 hits in 5 IP. They are technically still in it, just 4 games out of a Wild Card spot, but they're just 7-13 over the last 20.

Padres at Giants projected starters

RHP Yu Darvish vs. RHP Logan Webb

Darvish (1-3, 6.51 ERA) makes his seventh start. He has a 1.34 WHIP, 3.6 BB/9 and 7.5 K/9 over 27 2/3 innings.

  • Last start: No-decision, 4 IP, 3 ER, 3 H, 2 BB, 5 K in 10-5 win in 11 innings at Arizona Diamondbacks Tuesday
  • Last 5 starts vs. Giants: 0-2, 6.66 ERA, 1.52 WHIP, 30 K in 25 2/3 IP

Webb (10-8, 3.24 ERA) makes his 25th start. He has a 1.25 WHIP, 2.1 BB/9 and 10.1 K/9 through 147 1/3 innings.

  • Last start: Win, 6 IP, 1 ER, 7 H, 0 BB, 10 K in 8-1 win at Pittsburgh Pirates Tuesday
  • Last 5 starts vs. Padres: 1-2, 3.90 ERA, 1.53 WHIP, 23 K in 30 IP
  • 2 starts vs. SD this year: 0-1, 3.46 ERA, 1.23 WHIP, 13 K in 13 IP

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Padres at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1 p.m. ET.

  • Moneyline (ML): Padres +105 (bet $100 to win $105) | Giants -125 (bet $125 to win $100)
  • Run line (RL)/Against the spread (ATS): Padres +1.5 (-190) | Giants -1.5 (+155)
  • Over/Under (O/U): 7 (O: -120 | U: +100)

Padres at Giants picks and predictions

Prediction

Padres 7, Giants 6

Moneyline

The weather conditions -- detailed below -- favor the hitters, and that favors the Padres. Webb is great, but he has a 5.18 ERA over his last 7 GS. The Padres pummel him as well. Darvish is a shell of himself at age 38, but if this becomes a slugfest, give me the PADRES (+105).

Run line/Against the spread

I'll stick with the value on the ML, and there's upside with the total.

PASS.

Over/Under

It's expected to be a little chilly Monday evening at 63 degrees, and that includes a 22-mph breeze to straightaway center. With a couple of struggling starters, the OVER 7 (-120) seems like a no-brainer.

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This article originally appeared on Sportsbook Wire: San Diego Padres at San Francisco Giants odds, picks and predictions

Reporting by Ryan Dodson, Sportsbook Wire / Sportsbook Wire

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