Kyle Shanahan: Brandon Aiyuk's return could be Week 5, could be Week 10, won't be Week 1

The 49ers don’t know for sure when wide receiver Brandon Aiyuk will be ready to return from last season’s knee injury. But it should be around the middle of the season.

Head coach Kyle Shanahan said today that there’s still a range of potential outcomes, but Week Six is a potential target date he’s thinking of, not just for Aiyuk to make his 2025 debut, but also for quarterback Kurtis Rourke and safety Malik Mustapha, both of whom are also recovering from knee injuries.

“I kind of view all those guys around the same time, whether it’s Mustapha, whether it’s Rourke, or whether it’s Brandon,” he said. “I always see them around Week Six, which means that could be Week 10, it could be Week Five, but that’s the area where I start thinking about it, which is a long ways away. I know it’s not W