Key Takeaways

Childhood cancer survivors over age 50 had a threefold higher mortality risk compared with the general population, primarily from new cancers.

Survivors had a twofold higher risk of chronic health conditions, tripling for the risk of multiple conditions, compared with their siblings.

Radiation therapy accounted for 40% of the risk of new cancers, but chemotherapy had no significant associations with late effects.

Older adults who survived childhood cancers continue to die earlier, have more new cancers, and have worse health outcomes compared with the general population, a new analysis of an ongoing study showed.

Survivors older than 50 had a threefold greater risk of dying within 5 to 15 years, most often from development of new cancers. Childhood cancer survivors had m

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