Oregon has had a tough run lately. The state is bracing for painful federal cuts due to President Donald Trump’s recently passed budget bill. Layoffs at Intel and rising unemployment are contributing to a grim economic outlook. And Portland’s national reputation , battered in recent years by scenes of riots and public drug use, still faces a long road to recovery.

But Oregon’s most famous entrepreneur and his wife have placed a blockbuster bet on the state just when it needs it most.

Nike co-founder Phil Knight and his wife, Penny, are committing $2 billion over 10 years to OHSU’s Knight Cancer Institute with a bold mandate to accelerate research, revolutionize treatment and ultimately end cancer. Billed as the single largest gift ever to a university, the donation comes as t

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