TOPLINE:

In symptomatic adults with a coronary artery calcification (CAC) score of zero, elevated levels of low-density lipoprotein (LDL) cholesterol were associated with increased risks for noncalcified plaques and future coronary heart disease events, especially in those younger than 45 years.

METHODOLOGY:

Atherosclerosis is noncalcified in early stages, so a zero CAC score — especially in younger people — can obscure early disease and delay prevention.

Researchers conducted a cohort study in Denmark to investigate whether high levels of LDL cholesterol could predict the presence of noncalcified plaques and the risk for future cardiovascular events.

They included 23,777 adults (median age, 54 years; 61% women) who underwent coronary CT angiography between January 2008 and May 2021 d

See Full Page