TOPLINE:
Higher leukocyte counts, predominantly within the normal range, independently predicted new-onset diabetes in individuals with HIV infection , potentially identifying an increased risk for diabetes up to 10 years before diagnosis.
METHODOLOGY:
Researchers examined the association between blood leukocyte counts and the risk for new-onset diabetes among individuals of the Swiss HIV Cohort Study from January 2000 to August 2023.
They included 732 people with HIV infection and diabetes (cases) and 2032 matched control individuals with HIV infection but without diabetes. The median age of all individuals was 54 years, and both groups consisted of approximately 78.7% men.
New-onset diabetes was defined using the Expert Committee on the Diagnosis and Classification of Diabetes Mel