TOPLINE:

Severe deficiency of vitamin D (< 25 nmol/L) has been associated with a significantly increased risk for cataracts, particularly in people younger than 50 years.

METHODOLOGY:

Researchers examined cross-sectional and longitudinal associations between serum levels of 25-hydroxyvitamin D and the risk for cataracts, using data from the UK Biobank.

The cross-sectional analysis included 442,255 participants with data on serum levels of vitamin D; among them, 427,923 participants (mean age, 56.2 years; 53.6% women) without cataracts at baseline were followed up for an average duration of 10.8 years in the longitudinal analysis.

Based on serum levels of vitamin D at baseline, participants were categorized into those with severe deficiency (< 25 nmol/L), moderate deficiency (25-49.9 n

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