The Lost Promise of Lenacapavir

The Trump administration is throwing away a chance to end HIV worldwide.

Protesters carry mock coffins along a street. August 25, 2025, 4:21 PM Comment icon View Comments ( )

For the last two decades, the global distribution and ease of access for antiretroviral (ARV) drugs have transformed HIV from a death sentence to a manageable disease and prevented tens of millions of new infections when used as pre-exposure prophylaxis (PrEP). The remarkable new drug lenacapavir is a novel, first-in-class ARV that targets the HIV capsid, a protein shell that carries the viral genome. The capsid undergoes a process called uncoating, which allows the viral genome to be replicated and new virus particles to be produced. Lenacapavir blocks both the uncoating a

See Full Page