The top four seeds in action on Wednesday at the U.S. Open advanced to the third round in New York, while six seeded players lost and another withdrew.

Second-seeded Carlos Alcaraz of Spain breezed past Italy's Mattia Bellucci 6-1, 6-0, 6-3. No. 4 Taylor Fritz produced a 4-6, 7-6 (3), 6-2, 6-4 win over South Africa's Lloyd Harris. No. 7 Novak Djokovic of Serbia, a four-time U.S. Open champion, rallied past American Zachary Svajda 6-7 (5), 6-3, 6-3, 6-1, and No. 6 Ben Shelton dumped Spain's Pablo Carreno Busta 6-4, 6-2, 6-4.

Meanwhile, No. 5 seed Jack Draper was forced to withdraw due to an arm injury, while No. 11 Holger Rune of Denmark, No. 12 Casper Ruud of Norway, No. 16 Jakub Mensik of the Czech Republic, No. 18 seed Alejandro Davidovich Fokina of Spain and No. 30 Brandon Nakashima w

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