The Pittsburgh Pirates (59-76) and the Boston Red Sox (75-60) open a 3-game interleague series Friday at Fenway Park in Boston. First pitch is scheduled for 7:10 p.m. ET (MLB Network). Let's analyze BetMGM Sportsbook's MLB odds around the Pirates vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Red Sox won 3-0 in 2024

The Pirates split an entertaining 4-game series in St. Louis Monday through Thursday, falling 4-1 in the series finale against the Cardinals as slight underdogs (+105) as the Under (8.5) cashed for the second straight game. Despite the loss, the Bucs are still 6-2 in the past 8 games.

Pittsburgh's lone run Thursday came courtesy of a solo HR by OF Tommy Pham in the top of the first inning, as it

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