BUFFALO, N.Y. — A 6-year-old who was diagnosed with a rare form of leukemia is in remission and ready for first grade after receiving an innovative cancer treatment at Roswell Park Comprehensive Care Center .

On April 29, 2024, Bryn Ailinger was diagnosed with precursor B-cell acute lymphoblastic leukemia. Roswell Park says because her cancer cell carried a rare and aggressive mutation, TCF3-HLH, standard chemotherapies and surgeries didn't work.

"You think the worst immediately,” said Justin Ailinger, Bryn’s father. “I didn’t know if I was going to have a daughter by the end of the year."

Bryn's care team at Roswell Park recommended CAR T-cell therapy, a form of treatment that extracts T cells from a patient's blood and engineers them to recognize and kill cancer cells. The cells are

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