Key Takeaways

A single dose of RSV vaccine provides substantial protection for two seasons in a row

However, effectiveness waned slightly between the seasons

These results show that people might need a booster at some point, researchers say

WEDNESDAY, Sept. 3, 2025 (HealthDay News) — A single dose of RSV vaccine might protect seniors for two cold and flu seasons in a row, a new study says.

Vaccination reduced seniors’ risk of hospitalization by 58% during two RSV seasons, researchers reported Aug. 30 in the Journal of the American Medical Association .

“These results clearly demonstrate that the RSV vaccines prevent hospitalizations and critical illness due to RSV infection among older Americans,” said principal investigator Dr. Wesley Self , senior vice president for clinica

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