Alarms went off earlier in the week as San Francisco 49ers star running back, Christian McCaffrey, suddenly appeared in the injury report. He also missed the Friday practice. As the team prepares to face divisional rivals Seattle Seahawks, everyone is wondering if he will play in Week 1 of the 2025 NFL season.

McCaffrey will in fact play against the Seahawks. Reported by Adam Schefter of ESPN, CMC is “good to go.” The 49ers will have their running back taking the field, lining up alongside Brock Purdy.

It was rumored that McCaffrey was heavily involved in the Saturday walkthrough, potentially having a big role in the game, meaning he wouldn’t be limited. All in all, CMC will make his season debut today at Lumen Field.

Will Brock Purdy have other weapons return?

Wide receiver Jauan Jenn

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