The San Francisco 49ers travel the West Coast north to Seattle on Sunday for a date with the Seahawks to kick off their 2025 season. The game is scheduled to start at 4:05 p.m. ET (1:05 p.m. PT) with TV coverage on FOX and streaming on-demand .

How to watch 49ers vs. Seahawks on TV and stream the game on FOX:

When: Sunday, Sept. 7 at 4:05 p.m. ET (1:05 p.m. PT)

Where: Lumen Field, Seattle, Wash.

TV channel: FOX

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