The first Sunday of the 2025 NFL season concludes with a rematch of last year's AFC Divisional Round thriller as the Baltimore Ravens visit the Buffalo Bills at 8:20 p.m. ET on Sunday Night Football. After losing at Baltimore in Week 4 last season, the Bills exacted revenge in the playoffs by posting a 27-25 victory at home. However, the Ravens have won seven of the 11 regular season meetings between the clubs.

Another big matchup in Week 1 features an NFC North showdown in which the Green Bay Packers host the two-time reigning division champions Detroit Lions at 4:25 p.m. ET at Lambeau Field. The Packers own a 106-78-7 advantage in the all-time series but lost both matchups against the Lions last year, including a 24-14 setback at home in Week 9.

There also is a full 15-game

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