The pressure starts on Day 1 for the Cincinnati Bengals when they travel to Cleveland to open the 2025 NFL regular season on Sunday. Cincinnati failed to make the playoffs last year despite a near-MVP year by quarterback Joe Burrow. The Bengals, who closed 2024 by winning their final five games, will face a Cleveland Browns team that named Joe Flacco its Week 1 starter. The Bengals are 5.5-point favorites, but Burrow is just 3-5 in his career versus Cleveland, while Flacco hasn't faced Cincy since 2022.

Dolphins vs. Colts (-1) has the lowest Week 1 NFL spread as Daniel Jones will make his team debut against Tua Tagovailoa and Miami. Other slim NFL lines include Buccaneers vs. Falcons (+1.5) and 49ers vs. Seahawks (+1.5). Which team has value to include in Week 1 NFL bets, and which side o

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