Shohei Ohtani homered twice and Los Angeles starting pitcher Clayton Kershaw took a shutout into the sixth inning and this time the Dodgers held on to avoid a series sweep, beating the host Baltimore Orioles 5-2 on Sunday afternoon.
Mookie Betts also homered and drove in another run with a ninth-inning single.
The Dodgers (79-64) ended a 1-5 road trip and remained atop the National League West.
The Orioles (66-77) had won with ninth-inning walk-off stunners in the first two games of the series, including using a four-run ninth inning Saturday.
Michael Conforto joined Ohtani and Betts with two hits for the Dodgers.
Emmanuel Rivera, who had Saturday night's game-winning single, notched two of Baltimore's eight hits. The Orioles' five-game winning streak ended, with their batters strikin