NFL Research spotlights the best nuggets from each slate of games. Here are the most eye-popping statistical accomplishments from Week 1 of the 2025 NFL season.

1) Ravens have historic night in loss to Bills

Lamar Jackson had a near-perfect passer rating and ran for 70 yards and a score, Derrick Henry totaled over 170 yards and two touchdowns and the Ravens held a 15-point lead with four minutes remaining on Sunday Night Football . The Bills won 41-40.

The Ravens are the first team in NFL history to score at least 40 points and rush for 235 yards and lose that game. Teams were 277-0 including playoffs prior to their loss.

For John Harbaugh, it was the eighth time his team lost a game in which they held a fourth quarter lead of at least eight points. No other coach since 2000 has

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