The Week 3 college football schedule is one of the best of the season as many teams jump into conference play, while a few marquee non-conference games are on the slate as well. Tennessee and Georgia are off to fast starts, and now the SEC contenders meet in Knoxville on Saturday with the latest Week 3 college football odds listing the Bulldogs as 4.5-point favorites. Another SEC showdown features LSU (-9.5) vs. Florida.

Texas A&M, meanwhile, steps out of conference play to take on Notre Dame, and the Irish are listed at -6.5 in the latest Week 3 college football spreads. USF, fresh off of shocking Florida, will try to pull off another Sunshine State stunner as the Bulls take on Miami (-16.5.). Before locking in any college football picks for Week 3 of the 2025 season for those games or o

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