The Blue Jays have taken a blow with the loss of Bo Bichette to a sprained left knee , but they might be getting some serious help soon.

Anthony Santander, the team’s biggest free-agent acquisition of the off-season, finally began a rehab assignment with the Triple-A Buffalo Bisons on Thursday, serving as the designated hitter and batting second against Washington’s top affiliate, the Rochester Red Wings. And he got it going with a bang.

In the switch-hitter’s first game since May 29, when he was finally placed on the injured list after playing hurt for three weeks, Santander homered in his third plate appearance against former big-leaguer Adrian Sampson, a 396-foot drive to right field.

It was a welcome sight for Santander, who suffered a subluxation of his left shoulder when h

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