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Knee pain may be one of the most common mobility issues in the U.S. Whether it’s age-related wear, arthritis, or the aftermath of intense training, sore knees slow everything down. The market is full of joint supplements – the real challenge is figuring out which ones actually deliver on cartilage support, inflammation control, and long-term knee function.

That’s exactly what this list is built for. Reviewers for this article broke down more than 40 of the top joint supplements of 2025, narrowing the field to the formulas with clinical backing, smart dosing, and ingredients specifical

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