Kyle's favorite WR vs. CB matchups to exploit for Week 2 of 2025 - DFS wide receivers to target on DraftKings and FanDuel. These WR/CB matchups are GPP and cash game opportunities.

Welcome to the Wide Receiver Matchups to Target column for Week 2 of the 2025 NFL season. We're now working with a tiny one-game sample size in 2025, so we'll factor that in while giving more weight to other factors like implied totals, projected pace, and Vegas lines. Week 1 wasn't pretty for a lot of top-tier receivers, but we're tackling Week 2 to come back with a vengeance in DFS lineups.

To identify the best plays, we’ll use Pro Football Focus (PFF) WR/CB matchup grades to highlight receivers in favorable spots, with an eye toward those most likely to hit the 3x DraftKings multiplier that’s crucial in DFS

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