Week 1 of the 2025 NFL season is in the books, and Week 2 kicked off on Thursday. While we'd love for top players to stay healthy all season long, that unfortunately is rarely the case. That's especially true for Week 2, as there are plenty of injuries to star players that you need to be aware of. If you're interested in NFL betting , make sure to stay up to date on all the NFL injury news before you place any wagers at top sportsbooks .

Here, we break down the biggest NFL injuries to know ahead of 15 games on Sunday and Monday, including how lines have shifted according to the latest SportsLine consensus odds , which uses the latest data and odds from top sportsbooks .

New York Giants vs Dallas Cowboys (1 p.m. ET)

DAL CB DaRon Bland (foot, out)

NYG OT Andrew Thomas

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