When popular Italian restaurant Fresco by Scotto launches Saturday brunch with a live DJ for the first time in October, it might be a celebration of something precious in Midtown — a 10-year lease renewal with a simpatico landlord.

Fresco co-owner Rosanna Scotto, also known for her Channel 5 gig on “Good Day New York,” said 485 Madison Avenue owners Jack Resnick & Sons “really worked with us” on the deal. (Resnick was represented in-house in the renewal by Brett Greenberg and Adam Rappaport. Savills’ Ken Ruderman and Jeff Lagowitz represented Fresco.)

Scotto, who declined to discuss terms, said, “The Resnicks are part of our family.” Her actual family — including mother Marion and Rosanna’s son and daughter LJ and Jenna Ruggiero — opened Fresco in 1993. Since then, its pretty dining roo

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