Mac Jones threw three touchdown passes as Brock Purdy's replacement and the visiting San Francisco 49ers held off the New Orleans Saints 26-21 on Sunday afternoon.
Jones made his debut for the 49ers (2-0) in place of Purdy, who is sidelined by a toe injury, and completed 26 of 39 for 279 yards.
Spencer Rattler matched Jones' three touchdown passes while completing 25 of 34 for 206 yards and Alvin Kamara rushed for 100 yards on 21 carries for the Saints (0-2).
On the first possession of the third quarter, Jones fumbled when hit by Chris Rumph II and Demario Davis recovered for New Orleans at the San Francisco 47. Ten plays later, Rattler threw a 3-yard touchdown pass to Rashid Shaheed to trim the 49ers' lead to 16-14.
San Francisco responded with a drive that ended with Eddy Pineiro's 4