Key takeaways:
Head and neck cancer trials with no statistically significant results got published 11 times less often as those with significant findings.
Trials deemed incomplete also had higher likelihood of nonpublication.
An analysis of head and neck cancer trials identified two factors that strongly correlated with publication bias.
Clinical trials that did not yield statistically significant results were 11 times less likely to be published than those with significant results. Trials deemed incomplete — such as those that had been terminated early or withdrawn, or those with unknown status — were three times less likely to be published as trials that had been completed.
“Publication bias is not limited to head and neck cancer clinical trials. This is a widespread issue that ca