Buffalo Bills quarterback Josh Allen (17) looks to throw a pass as Miami Dolphins safety Marcus Maye (26) gives pressure in the fourth quarter at Highmark Stadium in Orchard Park, New York.

The Miami Dolphins (0-2) and the Buffalo Bills (2-0) meet on Thursday Night Football. Kickoff from Highmark Stadium in Orchard Park, New York, is scheduled for 8:15 p.m. ET (Prime Video). Let's analyze BetMGM Sportsbook's NFL odds around the Dolphins vs. Bills odds and make our expert NFL picks and predictions for the best bets.

Miami has dropped back-to-back games to open the season after falling 33-27 to the New England Patriots Sunday as a 2.5-point home favorite. QB Tua Tagovailoa went 26-of-32 for 315 yards with 2 TDs and 1 INT. WR Tyreek Hill led the team with 6 receptions for 109 yards.

Buffalo enters undefeated after pummeling the New York Jets 30-10 Sunday, covering as a 6-point road favorite. QB Josh Allen went 15-of-25 for 148 yards while rushing for 59. RB James Cook carried the ball 21 times for 132 yards and 2 TDs.

The Bills have beaten the Dolphins in each of their past 6 meetings, including both matchups last season.

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Dolphins at Bills odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Wednesday at 11:22 a.m. ET.

  • Moneyline (ML): Dolphins +575 (bet $100 to win $575) | Bills -800 (bet $800 to win $100)
  • Against the spread (ATS): Dolphins +12.5 (-110) | Bills -12.5 (-110)
  • Over/Under (O/U): 49.5 (O: -110 | U: -110)

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Dolphins at Bills key injuries

Dolphins

  • C Aaron Brewer (hip) questionable
  • CB Storm Duck (ankle) questionable
  • DT Benito Jones (oblique) questionable
  • S Ifeatu Melifonwu (calf) questionable
  • DE Chop Robinson (knee) questionable
  • WR Jaylen Waddle (shoulder) questionable
  • TE Darren Waller (hip) questionable
  • WR Malik Washington (thumb) questionable

Bills

  • CB Taron Johnson (quadriceps) questionable
  • LB Matt Milano (pectoral) questionable
  • DT Ed Oliver (ankle) questionable
  • LB Shaq Thompson (hamsting) questionable

Dolphins at Bills picks and predictions

Prediction

Bills 31, Dolphins 21

Moneyline

PASS.

There is no value on the Bills (-800) to win this matchup.

Against the spread

LEAN DOLPHINS +12.5 (-110).

While the Dolphins remain winless, they looked much improved offensively last week. They still have plenty of room to grow and should not be expected to win this game, but with a 12.5-point spread, they have what it takes to cover on the road.

The Bills have the firepower to break the game open, but they have also shown flashes of inconsistency through their first 2 outings. Allen, who injured his nose last week, generated little offense through the air, forcing the team to lean on Cook in the run game. While Buffalo is one of the NFL’s early juggernauts, the spread is too wide to back it with confidence.

Over/Under

BET OVER 49.5 (-110).

The Bills have scored 71 points through their first 2 games, putting up at least 31 in each. They have allowed 50 combined points and now face a Dolphins team more than capable of reaching the end zone.

The Dolphins have allowed 33 points in both of their games this season, each to opponents much worse offensively than the Bills. They scored 27 points last week, showcasing their ability to move the ball on offense. While the Bills will carry the majority of the load Thursday, the Dolphins will need to find the end zone a few times to help the Over hit.

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This article originally appeared on Sportsbook Wire: Miami Dolphins at Buffalo Bills odds, picks and predictions

Reporting by Seth Orlemann, Sportsbook Wire / Sportsbook Wire

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