The Arizona Cardinals will battle the San Francisco 49ers in a Week 3 battle at Levi Stadium in Santa Clara, California. The Cardinals barely escaped with a win over the Carolina Panthers. Conversely, the Niners defeated the New Orleans Saints, with the defense making a game-winning play to hold serve.

Both teams are dealing with injuries, which makes any Cardinals vs. 49ers bold predictions even more difficult. Yet, these Week 3 predictions will take into account what is likely to happen, given the teams' history and who is likely to play.

San Francisco is currently the 2.5-point favorite to beat Arizona, according to FanDuel. Amazingly, both teams are 2-0 and are enduring many challenges. The Cardinals impressed with a road win over the Saints before clipping the Panthers. The

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