Week 3 of the 2025 NFL season is set to kickoff Thursday night, which means it's time to take a look at what injuries could play a key role across the third week of the new campaign.

The San Francisco 49ers could potentially get quarterback Brock Purdy (left shoulder/toe) back in Week 3 with head coach Kyle Shanahan saying Purdy "has a chance" to play this week . With most squads returning to the practice field on Wednesday, it's a great time to check in on the initial injury reports. Below, we'll provide the latest from those reports while also getting a last look and a check in on the game statuses for Thursday's AFC East rivalry clash between the Miami Dolphins and the Buffalo Bills .

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