Arizona (2-0) at San Francisco (2-0)

Sunday, 4:25 p.m. EDT, Fox.

BetMGM NFL Odds: 49ers by 2 1/2.

Against the spread: Cardinals 1-1; 49ers 2-0.

Series record: 49ers lead 36-31.

Last week: Cardinals beat Panthers 27-22; 49ers beat Saints 26-21.

Last meeting: Cardinals beat 49ers 47-24 at Glendale, Ariz., Jan. 5, 2025.

Cardinals offense: overall (24), rush (13), pass (27), scoring (11).

Cardinals defense: overall (21), rush (6), pass (26), scoring (10).

49ers offense: overall (8), rush (22), pass (6), scoring (18).

49erss defense: overall (6), rush (13), pass (6), scoring (7).

Turnover differential: Cardinals plus-1; 49ers even.

Cardinals player to watch

Edge rusher Josh Sweat made his first big play as a member of the Cardinals when his strip-sack of Panthers QB Bryce Young res

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