Southern California and Michigan State have met in the Rose Bowl Game before, but they'll meet for the first time as Big Ten foes in Week 4.
USC is rolling at 3-0, averaging 55 points per game − second-best in FBS − while the total offense of 604 yards per game is tops in the country. The Trojans opened Big Ten play with a win over Purdue. Michigan State also enters with three wins to start the season, including a thrilling overtime win against Boston College in Week 2.
The Saturday, Sept. 20 matchup will mark the first meeting since 1990 for the two teams, and the first time to Los Angeles for Michigan State since 1978. With the Trojans and Spartans facing each other, it's a battle embedded in Greek mythology, and the victor of the college football Trojan War will be 4-0.
Stream Michigan State vs USC on Fubo (free trial)
Here's how to watch USC vs. Michigan State, including time, TV schedule, live streaming info and game odds:
What TV channel is USC vs Michigan State on today?
- TV: FOX
- Streaming: Fox Sports app | Fubo (free trial)
USC and Michigan State will air nationally on Fox in Week 4 of the 2025 college football season from Los Angeles Memorial Coliseum in Los Angeles. Jason Benetti (play-by-play) and Robert Griffin III (analyst) will be on the call, while Alexa Landestoy is the sideline reporter.
Streaming options include the Fox Sports App and Fubo, the latter of which offers a free trial to potential subscribers.
USC vs Michigan State time today?
- Date: Saturday, Sept. 20
- Time: 11 p.m. ET
It will be a late kickoff as Michigan State at USC starts at 11 p.m. ET (8 p.m. local) from Los Angeles Memorial Coliseum on Saturday, Sept. 20
USC vs Michigan State predictions, picks, odds
Odds courtesy of BetMGM as of Wednesday, Sept. 17:
- Spread: USC (-18.5)
- Over/under: 55.5
- Moneyline: USC (-600); Michigan State (+600)
- Prediction: USC 41, Michigan State 20
The Trojan offense continues to fire on all cylinders and stay undefeated heading into a massive matchup at Illinois in Week 5.
This article originally appeared on USA TODAY: What channel is Michigan State vs USC on today? Time, TV schedule to watch Week 4 game
Reporting by Jordan Mendoza, USA TODAY / USA TODAY
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