The Michigan State Spartans (3-0, 0-0 Big Ten) and the USC Trojans (3-0, 1-0) meet Saturday at the Los Angeles Memorial Coliseum. Kickoff is scheduled for 11 p.m. ET (FOX). Let's analyze BetMGM Sportsbook's NCAA football odds around the Michigan State vs. USC odds and make our expert college football picks and predictions for the best bets.

The all-time series is tied 4-4, but this is the first meeting since Dec. 31, 1990, in the Sun Bowl. Michigan State won that afternoon 17-16. This is the first regular-season meeting since Sept. 7, 1987, in East Lansing, a 27-13 victory by Sparty. USC hasn't topped Michigan State since Sept. 29, 1978, the last time these teams met at The Coliseum.

Michigan State has won all 3 games to date, but it is 0-3 against the spread (ATS). The Spa

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