Two top five Big Ten teams collide on Saturday night, when the Illinois Fighting Illini make the short trip to Bloomington for a potentially CFP-deciding matchup.

After returning a boatload of talent from last year’s 11-win team, Indiana (-182) enters this game against Illinois (+170) as a 4.5- point spread home favorite.

Meanwhile, the books expect a high-scoring affair, with the over/under sitting at 52.5 points.

Can Coach Curt Cignetti and the Hoosiers prove the doubters wrong this weekend, or will Luke Altmyer and company take one step closer to their first College Football Playoff appearance?

Illinois vs. Indiana Predictions and best bets

*Note: Odds are based on the best value our experts find as of publication; check lines closer to game time to ensure you get the best od

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