WHAT TO KNOW
* Programming note: Immediately after the Week 3 game ends, watch “49ers Postgame Live” on NBC Sports Bay Area or stream the show in the NBC Sports app for full reaction, analysis and interviews. * The 49ers improved to 3-0 on the 2025 NFL season after a 16-15 win over the Arizona Cardinals on Sunday at Levi’s Stadium * Mac Jones made his second 49ers start in place of Brock Purdy and completed 27 of 41 passes for 284 yards with one touchdown and one interception, including a 10-play, 63-yard final drive to set up Eddy Piñeiro’s game-winning field goal. * Ricky Pearsall was the 49ers’ leading receiver, recording 117 yards on 8 receptions and averaging 14.6 yards per catch. * Star edge rusher Nick Bosa was ruled out of the game in the first quarter with a knee injury.
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